000			01927nam 2200373| 4500
001			84378
005			20210310143535.0
010			_a978-3-642-35958-3 _dcompra
090			_a84378
100			_a20190128d2015 k||y0pory50 ba
101			_aeng
102			_aUS
200			_aAn operator semigroup in mathematical genetics _bDocumento eletrónico _fAdam Bobrowski, Marek Kimmel
210			_aBerlin, Heidelberg _cSpringer _d2015
215			_aVI, 88 p. _cil.
225			_aSpringerBriefs in Mathematical Methods
300			_aColocação: Online
303			_aThis authored monograph presents a mathematical description of the time evolution of neutral genomic regions in terms of the differential Lyapunov equation. The qualitative behavior of its solutions, with respect to different mutation models and demographic patterns, can be characterized using operator semi group theory. Mutation and drift are two of the main genetic forces, which act on genes of individuals in populations. Their effects are influenced by population dynamics. This book covers the application to two mutation models: single step mutation for microsatellite loci and single-base substitutions. The effects of demographic change to the asymptotic of the distribution are also covered. The target audience primarily covers researchers and experts in the field but the book may also be beneficial for graduate students.
410			_x2365-0826
606			_aBiomatemática
606			_aTeoria dos operadores
606			_aEngenharia biomédica
606			_aGenética das populações _xModelos matemáticos
606			_aProbabilidades
680			_aQH323.5
680			_aQH455
700			_aBobrowski _bAdam
701			_933764 _aKimmel _bMarek _4070
801			_gRPC _aPT
856			_uhttps://doi.org/10.1007/978-3-642-35958-3
942			_2lcc _cF _n0